We all know probiotics are good for digestion—but what if the right probiotic could also help you feel calmer, think clearer, and even move more freely?

That’s the promise of Lactobacillus plantarum PS128™, a new kind of probiotic called a psychobiotic. Unlike traditional probiotics, psychobiotics support both gut health and mental wellbeing by influencing the powerful gut-brain axis, a communication network linking your digestive system to your brain.

In this article, we’ll explore what makes PS128™ different, how it works, and why it’s gaining attention from scientists, parents, and wellness seekers alike.

Introducing PS128™: A Psychobiotic Strain that works from the gut 

PS128™ is a patented strain of Lactobacillus plantarum that’s been studied in both animal and human trials for its ability to support mental wellness. It belongs to a unique class of probiotics known as psychobiotics—microbes that influence your brain and behavior through the gut-brain axis.

But here’s the key: PS128™ doesn’t cross into your brain. Instead, it works in your gut to naturally modulate neurotransmitters like dopamine and serotonin, the same brain chemicals involved in:

• Mood balance
  
  
• Focus and attention
  
  
• Motivation and energy
  
  
• Stress response
  
  
• Motor control
  
  

It’s a subtle, natural approach—not a stimulant, not a sedative. Just your gut microbiome doing what it does best: helping you feel more like yourself.

PS128™ and Clinical Studies: Science-Backed Benefits Beyond Digestion

PS128™ isn’t just theory—it’s one of the most researched psychobiotics on the market today, with studies supporting its benefits across multiple populations and health goals. Here’s a summary of what clinical and preclinical research has revealed:

Emotional Balance and Neuroprotection

In both animal and human studies, PS128™ has been shown to protect dopamine-producing neurons—critical for regulating movement, motivation, and mood. This makes it a promising option for individuals seeking natural emotional support or neuroprotective care.

Autism Spectrum Disorder (ASD)

Multiple trials, including randomized double-blind placebo-controlled studies with children, show that PS128™ can improve social behaviors, reduce anxiety, and enhance focus. In mouse models of autism, it also reduced hyperactivity and improved social interaction.

Parkinson’s Disease

In people with Parkinson’s, PS128™ has helped reduce tremors, stiffness, and sleep disturbances, and supported better motor control. Notably, when paired with deep brain stimulation (DBS) in animal studies, it enhanced the effects on brain wave regulation.

Stress and Sleep Quality

In individuals with high stress levels or insomnia, daily supplementation with PS128™ over three months lowered cortisol, improved sleep quality, and enhanced overall life satisfaction.

Digestive Health and Constipation

PS128™ stimulates gut motility and mucin production, helping to relieve constipation and promote smoother, healthier digestion—even in individuals with slower bowel function.

Who Can Benefit from PS128™?

Here’s a look at who may benefit most from adding PS128™ to their daily routine:

- Individuals on the Autism Spectrum (ASD)

PS128™ has been studied in both children and adults with autism, with promising results.
It may support:

• Emotional regulation
  
  
• Improved focus and attention
  
  
• Better sleep quality
  
  

These effects are believed to stem from its ability to support dopamine and serotonin balance, which plays a key role in reward processing and behavior.

- People with Parkinson’s Disease

For those managing Parkinson’s, PS128™ offers a natural way to support neurological health.
Clinical studies suggest it may:

• Improve motor function
  
  
• Support motor function
  
  
• Enhance overall wellbeing
  
  

These benefits are linked to PS128™’s impact on dopamine signaling, a major factor in Parkinson’s-related movement challenges.

- Parents of Children with Attention Difficulties

Many families are exploring PS128™ as a non-pharmaceutical tool to help children who are easily distracted, overwhelmed, or emotionally reactive.
Used alongside healthy routines and behavioral therapies, PS128™ may help:

• Boost focus
  
  
• Support learning
  
  
• Promote a calmer, more balanced mood
  
  

While not a cure, it can be an effective part of a gut-brain wellness strategy.

Research suggests PS128™ may be particularly helpful for:

- People with High Stress or Low Focus

PS128™ has been shown to help reduce cortisol levels (the stress hormone), and early users report feeling calmer, more focused, and less reactive under pressure.

- Individuals on the Autism Spectrum (ASD)

Clinical trials in children and adults with autism have reported improvements in emotional regulation, anxiety, focus, and sleep quality. It may help enhance dopamine signaling, which plays a role in attention and reward.

- Individuals with Parkinson’s Disease

In studies involving Parkinson’s patients, PS128™ supported motor function and helped manage tremors, stiffness, and other movement challenges—again linked to its effect on dopamine balance.

- Parents of Easily Distracted or Overstimulated Children

Some families use PS128™ as part of a non-pharmaceutical approach to help children improve attention, emotional balance, and learning focus. While not a cure or replacement for therapy, it can be a powerful tool in the mental wellness toolbox.

A Natural Step Toward a Healthier Mind

Formulated with clinically effective levels of PS128™™ (60 billion CFUs), Neuralli™ MP is a medical food designed to support individuals with Autism Spectrum Disorder (ASD) and Parkinson’s Disease (PD) by targeting the gut-brain axis.

What Makes Neuralli™ MP Stand Out:

• Clinically studied dose: 60 billion CFUs of PS128™™ per serving
  
  
• Made in the USA: Manufactured with strict quality standards
  
  
• Third-party lab tested: Verified for purity and potency
  
  

When You Receive Neuralli™ MP:

• Keep it cold: PS128™™ is not shelf-stable—it must be refrigerated upon arrival
  
  
• Check the expiration date to ensure freshness and effectiveness
  
  

Whether you’re looking to enhance your child’s focus, manage stress naturally, or simply think and feel more clearly, PS128™™ offers a science-backed, gut-first solution to support mental wellbeing.

Neuralli™ MP doesn’t just mask symptoms—it works from within, helping you feel more focused, balanced, and like yourself again.