Neuralli MP is a medical food that provides 60B CFU of L. plantarum PS128, a Bened Life exclusive probiotic strain. It is intended for the specific dietary management of autism and Parkinson’s disease under the supervision of a health care provider.
Neuralli MP downloadable resources
Provider & patient fact sheets
PS128 clinical studies
L. plantarum PS128 is the most clinically studied probiotic strain for dietary management of autism. A single-arm study on Parkinson’s also suggests promising results for some patients taking PS128 as dietary management alongside their PD therapies. Read the peer-reviewed clinical studies of PS128 on these and other conditions.
Autism and other neurodevelopmental conditions
Significant improvements for Autistic children taking PS128, more than other probiotics (Real world study)
Overall improvement for autism patients taking both PS128 and oxytocin (RCT)
PS128 alleviated ADHD-like and other behaviors in Autistic children (RCT)
Anxious/depressed score improvements for Autistic preschoolers taking PS128 (RCT)
ADHD symptoms significantly decreased in children with Tourette syndrome taking PS128 (RCT)
Improvements observed in children with Rett's syndrome taking PS128 (RCT)
Parkinson’s Disease
Improved motor function and quality of life in Parkinson's patients taking PD treatment and PS128 (Single-arm study)
Major depressive disorder
Improvements in the depression scale and gut microbiota changes, including an increase in the average relative abundance of Akkermansia compared to baseline, were observed. (Single-arm study)
The effects of PS128 versus placebo in MDD were studied. (RCT)
Parkinson’s Disease
Improved motor function and quality of life in Parkinson's patients taking PD treatment and PS128 (Single-arm study)
Major depressive disorder
Improvements in the depression scale and gut microbiota changes, including an increase in the average relative abundance of Akkermansia compared to baseline, were observed. (Single-arm study)
The effects of PS128 versus placebo in MDD were studied. (RCT)
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Additional resources
Additional resources
Videos
Excerpts from "The Gut Microbiome in the Gut-Brain Axis and the Role of Probiotic
PS128 in Autism", Autism Parenting Summit October 2023, shared with permission.
Presenter: Noelle Patno, PhD, Chief Science Officer, Bened Life.
Excerpts from "The Gut Microbiome in the Gut-Brain Axis and the Role of Probiotic PS128 in Autism", Autism Parenting Summit October 2023, shared with permission. Presenter: Noelle Patno, PhD, Chief Science Officer, Bened Life.
Podcasts
PS128 preclinical studies
L. plantarum PS128 regulated levels of dopamine in the brain in rats
PS128 enhanced dopamine and BDNF in the brain in mice
PS128 regulated dopamine and serotonin levels, improved anxiety-like behaviors in germ-free mice
PS128 lowered anxious behaviors and regulated related brain dopamine and serotonin in mice
PS128 increased gut motility and intestinal serotonin in mice
L. plantarum PS128 did not induce adverse effects in a battery of tests and passed standard safety tests
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