Do you persistently feel sad, hopeless, not interested in anything, or stressed? A feeling of suffocation leads to a variety of breakdowns. You are not alone!

Approximately 5% of adults suffer from depression, and 20 out of every 100 people develop depression at some point in their lifetime, eventually becoming a significant public health concern worldwide.

There is no quick fix to negative thoughts since they can hit you when taking care of your family, at work, or during/after maternity. However, do you know this is happening because you have an inflamed body due to unhealthy gut?

The Gut and Major Depressive Disorder (MDD)

Called the Second Brain - having the second largest number of neurons besides our brain, our gut is connected to the brain via the Gut-Brain Axis (GBA), explaining why we have “butterflies” in our stomachs when we are nervous.

Unfortunately, it appears that low-grade chronic neuroinflammation plays a critical role in forming the basis for the interaction between stress, gut microbiota, and major depressive disorder (MDD).

Interestingly, research indicates that treating the gut with Neurobiotics like PS128™ can help reduce inflammation and balance gut microbiota, significantly improving the quality of life of those with depressive disorder.

Stressors in Life

Stress is a normal part of life -- but some changes in health, career, family, and lifestyle cause more anxiety than the others. Have you ever thought what are the stressors of your life?

We all wear many hats in our life, both men and women. A woman can be a mother to her children, an employee to the company, a manager to a team, a caregiver to seniors, or a wife to her husband. According to WHO, women are 2x more likely to be diagnosed with depression than men. Being a mom is a long journey for women, starting from pregnancy, going into labor, until the birth of the baby. However, the journey hasn’t yet ended - “postpartum blue” or “maternity blue” is preparing to take advantage of every opportunity to cause unstable emotions, resulting in postpartum depression.

Rarely, an extreme mood disorder called postpartum psychosis also may develop after childbirth. Differences in hormones, social roles, and life stress are slowly poisoning their mental health, eventually contributing to depression.

Men is in no better situation. Do you think only women develop depression? Assumptions about traditional gender roles are critical barriers to diagnosing men with depression. Why? Traditional masculines can make it even more challenging to acknowledge and express feelings, making them less likely to seek help for their symptoms.

Japan has a famous phenomenon highlighting the importance of tackling mental health - “May Blues” or “gogatsubyō”. A transition in life makes it hard to adapt, whether you are a fresh graduate, returning from maternity leave, or holiday/vacation. Entering or re-entering the workforce is a crucial factor causing depression. Internal stress (e.g., anxiety) + external environment (e.g., monsoon season) often lead us into a worse situation and, eventually, get out of hand.

How much do you score from self-quiz for depression? If you score more than five, then it is time to pay attention and love yourself.

Mood disorder is a class of severe mental illnesses describing all types of disorders like depression, anxiety disorder, bipolar, manic depression, etc. You might wonder: what is a mood disorder, and how do we distinguish between a “normal feeling down” and a “mood disorder”?

Emotions like anxiety, feeling down, unhappy, stressed, angry, etc., all can be related to daily stress and frustration, traumatic events, or one’s personality. The difference between a normal feeling down and a mood disorder is “frequency” and “time duration.”

Theoretically speaking, negative emotions will fade away with time; it won’t be a long-lasting emotion. If the emotion carries on, then there is a chance of developing into a emotional disorder.

Low levels of serotonin will cause depression, anxiety, insomnia, and other mood problems. Seeking medical advice is a general practice, but what if there is a natural therapy rather than a medication? PS128™ is a novel psychobiotic that balances the “happy hormones” like serotonin and cortisol, and other molecules that affect mind, mood, and movement.

Happier Gut, Healthier Mind

Can probiotics help with Major Depressive Disorder (MDD)?

Recently, probiotics have become a popular treatment for gut-related issues, as disruptions to gut microbiota balance may contribute to a wide range of health concerns, even mental health. One of the factors affecting your gut health is diet. An unhealthy diet destroys gut bacterial composition and reduces bacterial diversity and richness, resulting in gut inflammation.

Not all probiotics are equivalent; only specific researched strains like Neurobiotics have an impact on improving mental health symptoms. A medical probiotic can modulate neurotransmitters that affect appetite, mood, or sleep and reduce neuroinflammation in your body.

Interestingly, research indicates that Lactobacillus plantarum PS128™ appears to improve anxiety symptoms and reduce adverse reactions.

The Neurobiotic - L. plantarum PS128

Probiotics are live microorganisms, which can tip the balance of the gut microbiome, and are known for providing health benefits. But neurobiotic strains like L. plantarum PS128 - naturally isolated from the fermented vegetable Fu-Tsai - go further providing benefits for those with Autism, ADHD, Parkinson's disease, and Depression.

“Unlike pharmaceuticals merely overpowering our bodies’ functions, the fermented food-derived PS128 gently works with our microbiome.”

PS128™ clinical data on depression

The efficacy of PS128™ preclinical studies on depression was proven in a recent clinical study. After consuming PS128™, depressive severity in patients with MDD significantly ameliorated, and among them, nearly 3/4 are females.

Bened Life

Derived from the Latin root “benedicere”, which means “blessed” or “full of blessings”, the Bened Life team comes from all walks of life, united by a common mission to advance science, improve health, and build a sensory inclusive world. And KultureCity, an NGO for neurodiverse people, has been a partner for our dream.

Bened Life is dedicated to promoting neurological and mental health with pharma-grade brain probiotics, backed by over 30 years of research experience, and clinical studies. With Neuralli, we are making meaningful impact on individuals and families globally.

“Let’s have a world where one can thrive regardless of how one perceives the world -
a world where we all can all truly live a bened life.”

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Neuralli® MP

Each serving (2 caps.) of Neuralli MP contains 60 billion CFUs of PS128 - a specific amount one can’t get from eating food alone. Neuralli MP is a safe and natural product - it does not contain any additives and is free of 14 common allergens. It is also considered as "generally recognized as safe" (GRAS) to consume.

Regulate neurotransmitters

Reduce anxiety

Significantly improve
neurological disorders

All About Neuralli

How do I use the pills as a powder?

Swallowing the pills is not the only way to take Neuralli MP - you can also use the contents of the capsules in powder form. Neuralli MP capsules can be twisted and then pulled open.

Open the capsules over the cold food or drink that you wish to mix it with so you don’t lose any of the powder. We do not recommend mixing Neuralli MP powder into hot foods or liquids, as it will decrease the potency of Neuralli MP.

Mix thoroughly and consume within a few minutes for best results.

“The first and leading gut-brain medical probiotic from the United States for ADHD, Autism, Depression, and Parkinson’s.”

Neuralli MP can be taken as easy-to-swallow capsules or opened and mixed into cold liquids or foods.

Single - Neuralli MP

1 Bottle
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Twins - Neuralli MP

2 Bottles
60 capsules/bottle
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6-Pack - Neuralli MP

6 Bottles
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12-Pack - Neuralli MP

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Shipping Details

**VAT & custom duties not included, see checkout page for charges.
To see if Neuralli works for you, please consider 2-month trial or more.
Neuralli contains the unique neurologically active probiotic strain L. plantarum PS128.
PS128 was administered for 2 or more months in all but one clinical study**.

**In studies of people with neurological conditions.

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What People Say

Real reviews from real customers


Customer Service is fantastic, as is the product itself. Came really quickly! I ordered early in the morning, and got it in the evening the next day!!! Amazing! Benefits have been apparent as well. I have really bad anxiety, and all my meds weren't working, and giving me weird side effects. I pretty much gave up on using conventional medications and decided to just suck it up. Then I found a post on Reddit talking about how it helped someone with their anxiety and thought, what the heck, I will try it . Worst case scenario, I get GI benefits, best scenario it helps with my anxiety. I got the best case scenario, and the GI benefits! LOL. Anxiety is still there, but I can live with it , and not as debilitating as it used to be. Been taking it for about 2.5 months.



I have Complex Post-Traumatic Stress Disorder (C-PTSD) and Neuralli is helping me. I struggle with depression, anxiety, and mood regulation, and Neuralli boosts my baseline mood and reduces my anxiety, which makes it easier for me to regulate myself when triggered. For example, before Neuralli, a PTSD trigger might have caused anxiety that would register as a 9 on a scale of 1 to 10. With Neuralli, that same trigger might register as a 6 or 7. Since my nervous system isn't as overwhelmed, I can use tools learned in therapy to regulate myself. With Neuralli and talk therapy, I'm definitely making progress managing my C-PSTD. *For reference, I've been taking two capsules a day for five months, with no side-effects, and this is the only thing I'm taking for these issues.

Amanda V.


I've had such a dramatic change in my depression and overall attitude since starting to take Neuralli. I had initially tried it for a month and didn't notice any changes, but when I stopped taking it for a couple of weeks, I had a massive depression bout. When I started up again my mood dramatically improved again. It's been shocking to see how much impact it has on me.

J L.


It’s been amazing. I had problems sleeping for years and had emotional breakdowns often in presence of stress. After about a week I started sleeping 5 hours straight and after a month I notice less breakdowns.

L M.


I'm in STEM, and I normally wouldn't be caught dead making claims like this, but I must say, PS128 is the closest thing to happy pills I've ever found. I went from a chronically depressed person to an almost annoyingly happy person, while taking PS128. Thank you for everything.



I have been deeply depressed since losing my husband nearly a year ago and this product has helped me tremendously. I have not felt this well in many months. Thank you.


What People Say

So Thankful to Find This

[My daughter] said she feels more even-keeled, more positive, better rested and less anxious. I am noticing a significant improvement in her ability to handle stress which would normally result in meltdowns. This probiotic really seems to be making a difference for her.

K. T.

Honestly Life Altering

Amazing product. It has improved my mood tremendously and allowed me to find more joy in each day. Highly recommend. Worth every penny.

Laura N

More Laughter

We are only two weeks in, but I have seen an improvement in my son’s mood. I hear more laughter than I did before. So I am sure we are headed in the right direction.

Jennifer F

Thank You!

At one month in I am amazed at the positive benefits my body seems to be getting.

Barbara A.

Did you know…?

What is Neuralli MP?

Neuralli MP, as its name suggests, is a medical probiotic specific to neurological and mental health. Neuralli MP’s active ingredient, L. plantarum PS128, is able to provide clinically meaningful improvements for people with neurological conditions such as MDD. Neuralli MP is a medical probiotic because it is a medical food, which is intended for use under the supervision of a physician and provides dietary management for neurological conditions such as ASD, PD, MDD, and ADHD.

What are the ingredients in Neuralli MP?

Each serving (2 capsules) of Neuralli MP contains at least 60 billion CFU L. plantarum PS128. Other ingredients include microcrystalline cellulose, magnesium stearate, and silica. The vegetarian capsule is made of hypromellose.

Can my child take Neuralli MP? What is the dosage?

Children as young as 3 years of age have used 60 billion CFUs of PS128 per day in clinical studies. These children were under the supervision of physicians for their diagnosis of autism. Two capsules of Neuralli MP contain 60 billion CFUs of PS128.

Is Neuralli MP FDA approved?

The FDA approves drugs (or medicines). Neuralli MP is not a drug or medicine. It is a medical probiotic, which is a type of medical food.

L. plantarum PS128, derived from a fermented food, is affirmed as generally recognized as safe (GRAS).

What are the common side effects?

When taking Neuralli MP as directed (2 capsules containing 60 billion CFU of L. plantarum PS128), some people may experience mild gastrointestinal upset such as gas, bloating or stool changes for up to a week, just as when starting any new probiotic. In clinical studies of the PS128 probiotic with Autistic participants or patients with Parkinson’s disease, reports of adverse effects were very low. If side effects persist, we recommend consulting your health care provider.

How long will it take to notice results?

Noticeable results varies between individuals. 70% of people who took Neuralli MP for 2+ months improved their quality of life, based on 70 customer survey respondents. You may notice changes within the first week, or it may require 2 or more months to notice results, as evidenced by clinical studies of PS128.

Can I take Neuralli MP with other supplements or probiotics?

Neuralli MP can be taken with most other supplements or probiotics. Use caution when combining Neuralli MP with any other substance that affects levels of neurotransmitters such as serotonin. Contact your health care provider if you have any concerns about interactions with other products you are taking or if you have any health conditions.

How should I store Neuralli MP? Does it need to be refrigerated?

To keep your products maximally effective, store them in their original CSP bottles in the refrigerator. Be sure to keep Neuralli MP in its original bottle to limit the exposure of the capsules to humidity; do not store the capsules in a different container. Do not expose Neuralli MP to high heat or direct sunlight.

If you travel with Neuralli MP, always keep it in a cool, dry place. Storing a bottle at a consistent room temperature for up to one month will not impact the efficacy of the product.

Can Neuralli MP travel under high temperature if products are shipped from the US to Asia?

Neuralli MP can travel up to 2 weeks at room temperature or a few days at up to 99 °F (37 °C) will not impact its potency significantly. Each capsule of Neuralli is packed with more than 30 billion CFUs to account for any loss that may occur during transport and storage.

Local market presence

While we currently do not maintain physical stores in SG, JP, PH, and HK, we are actively exploring options to bring our products closer to you.

Neuralli MP has undergone extensive research and clinical studies and holds various certifications to ensure its excellence. Before making a purchase, feel confident knowing that our products are supported by experts in the field. For further details regarding the science behind Neuralli MP, click here. Have questions? Our dedicated online customer service team is here to provide you with all the assistance you need, ensuring a seamless shopping experience from start to finish.

Customer care

Your satisfaction and well-being are our highest priorities. Should you encounter any issues or have any concerns, our dedicated customer service team is here to assist you every step of the way. Feel free to reach out to us at [email protected] or, and we'll ensure your needs are addressed promptly and effectively. We are committed to delivering excellent service and aim to respond to all inquiries within three working days.

You can view more frequently asked questions here.

Further reading:


Can probiotics improve mental health?


Do probiotics help with anxiety?


Probiotics for stress