L. plantarum PS128 - published peer-reviewed research

​L. plantarum PS128 and Other Probiotics in Children and Adolescents with Autism Spectrum Disorder: A Real-World Experience

Significant improvements for autism patients taking PS128, more than other probiotics

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Probiotic and Oxytocin Combination Therapy in Patients with Autism Spectrum Disorder: A Randomized, Double-Blinded, Placebo-Controlled Pilot Trial

Overall improvement for autism patients from PS128 and oxytocin combination therapy

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Effects of L. plantarum PS128 on Children with Autism Spectrum Disorder in Taiwan: A Randomized, Double-Blind, Placebo-Controlled Trial

Alleviated ADHD and other symptoms of autism in children

Randomized Controlled Trial of Probiotic PS128 in Children with Tourette Syndrome

ADHD symptoms significantly decreased in children with Tourette syndrome taking PS128

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The Add-On Effect of L. plantarum PS128 in Patients with Parkinson's Disease: A Pilot Study

Improved motor function and quality of life in Parkinson's patients taking levodopa

Psychophysiological Effects of L. plantarum PS128 in Patients with Major Depressive Disorder: A Preliminary 8-Week Open Trial

Depressive thoughts, feelings, and other symptoms significantly decreased

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Effects of L. plantarum PS128 on Depressive Symptoms and Sleep Quality in Self-Reported Insomniacs: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial

Improved depressive symptoms and sleep quality

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Psychobiotic Supplementation of PS128 Improves Stress, Anxiety, and Insomnia in Highly Stressed Information Technology Specialists: A Pilot Study

Benefited anxiety, stress, and insomnia in highly-stressed office workers

Clinical Application Value of Lactobacillus Plantarum PS128 in Patients with Anxiety Disorders

Better outcomes and fewer adverse effects from PS128 + SSRI (citalopram) than with SSRI alone

Effect of Daily Oral L. plantarum PS128 on Exercise Capacity Recovery after a Half-Marathon

Faster split times and increased lower leg strength in recreational runners

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L. plantarum PS128 Improves Physiological Adaptation and Performance in Triathletes through Gut Microbiota Modulation

Benefits to exercise recovery and athletic performance in athletes

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The Beneficial Effects of L. plantarum PS128 on High-Intensity, Exercise-Induced Oxidative Stress, Inflammation, and Performance in Triathletes

Improved oxidative stress, exercise performance, and serum BCAA levels in athletes

L. plantarum PS128 prevents cognitive dysfunction in Alzheimer's disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis

PS128 protected against Alzheimer's disease in mice

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L. plantarum PS128 ameliorates 2,5-Dimethoxy-4-iodoamphetamine-induced tic-like behaviors via its influences on the microbiota-gut-brain-axis

PS128 regulated dopamine and reduced Tourette syndrome-like behavior in rats

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L. plantarum PS128 Alleviates Exaggerated Cortical Beta Oscillations and Motor Deficits in the 6-Hydroxydopamine Rat Model of Parkinson's Disease

PS128 was comparable and lasted longer than levodopa, DBS in improving Parkinson's indicators in rats

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L. plantarum PS128 alleviates neurodegenerative progression in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse models of Parkinson's disease

PS128 enhanced dopamine and BDNF, reduced Parkinson’s disease-like symptoms in mice

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Alteration of behavior and monoamine levels attributable to L. plantarum PS128 in germ-free mice

PS128 regulated dopamine and serotonin levels, improved anxiety-like behaviors

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Psychotropic effects of L. plantarum PS128 in early life-stressed and naïve adult mice

PS128 lowered behaviors of anxiety and depression, regulated related dopamine and serotonin in mice

L. plantarum PS128 Ameliorated Visceral Hypersensitivity in Rats Through the Gut-Brain Axis

PS128 ameliorated gastrointestinal pain and other symptoms in rats

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L. plantarum PS128 Promotes Intestinal Motility, Mucin Production, and Serotonin Signaling in Mice

PS128 increased gut motility and immune activity in mice

Toxicity Studies of L. plantarum PS128™ Isolated from Spontaneously Fermented Mustard Greens

PS128 was confirmed as safe and nontoxic in a battery of tests