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Significant improvements for Autistic children taking PS128, more than other probiotics (Real world study)
doi.org/10.3390/nu13062036
Overall improvement for autism patients taking both PS128 and oxytocin (RCT)
doi.org/10.3390/nu13051552
PS128 alleviated ADHD-like and other behaviors in Autistic children (RCT)
doi.org/10.3390/nu11040820
Anxious/depressed score improvements for Autistic preschoolers taking PS128 (RCT)
doi.org/10.1016/j.rasd.2023.102256
ADHD symptoms significantly decreased in children with Tourette syndrome taking PS128 (RCT)
doi.org/10.3390/nu13113698
Movement improvements using PS128 in Rett's Syndrome (RCT)
doi.org/10.1177/13623613231225899
Improved motor function and quality of life in Parkinson's patients taking PD treatment and PS128 (Single-arm study)
doi.org/10.3389/fnut.2021.650053
Improvements in the depression scale and gut microbiota changes, including an increase in the average relative abundance of Akkermansia compared to baseline, were observed. (Single-arm study)
doi.org/10.3390/nu13113731
The effects of PS128 versus placebo in MDD (RCT)
doi.org/10.1016/j.ajp.2024.104210
L. plantarum PS128 regulated levels of dopamine in the brain in rats
doi.org/10.1016/j.brainresbull.2019.07.027
PS128 enhanced dopamine and BDNF in the brain in mice
doi.org/10.3390/ijms24076794
PS128 regulated dopamine and serotonin levels, improved anxiety-like behaviors in germ-free mice
doi.org/10.1016/j.bbr.2015.10.046
PS128 lowered anxious behaviors and regulated related brain dopamine and serotonin in mice
doi.org/10.1016/j.brainres.2015.11.018
PS128 increased gut motility and intestinal serotonin in mice
doi.org/10.1007/s12602-021-09814-3
L. plantarum PS128 did not induce adverse effects in a battery of tests and passed standard safety tests
doi.org/10.3390/foods8120668
