Introducing Neuralli MP

Since 2012, medical science has exploded with new research into the gut microbiome. From gastrointestinal function, to weight gain, to food allergies, we now know that gut microbes have a powerful influence on our physical health. No wonder so many people choose to take probiotics.

But you might not know that the gut microbiome also plays a significant role in neurological and mental health. Levels of "happy brain hormones" like dopamine and serotonin can be influenced by certain probiotics and gut bacteria. These same neurotransmitters are imbalanced in certain neurological conditions like ASD and PD that also affect gut health.

Introducing Neuralli® MP (formerly Neuralli), the only probiotic medical food formulated to address the unique dietary needs of people with neurological conditions such as ASD and PD.

Each serving of Neuralli MP contains 60 billion CFUs of L. plantarum PS128, a unique gut-brain probiotic strain.   As PS128 transits through the gut, it alters the activity of neurons in the brain - specifically through effects on dopamine and serotonin in the brain, as observed in preclinical studies.

Since 2015 when our parent company Bened Biomedical introduced PS128 to the world, 35+ million servings have been sold worldwide. In the years since then, the neurological health benefits of PS128 have been studied in many human clinical trials. Neuralli MP stands on a rich history of PS128 science and helping people with neurological conditions.

Bened Life is committed to science and serving the neurodivergent community

Neuralli MP is the first gut-brain medical probiotic

If you’re not familiar with the many probiotic strains out there, you might think all probiotics are pretty much the same. Is there really any difference between Neuralli MP and yogurt with “live cultures” or a supplement for gut health?

There is!

First of all, Neuralli MP is a gut-brain probiotic. Its active ingredient is the live probiotic bacterial strain L. plantarum PS128. When the acid-resistant Neuralli MP capsule reaches your gut, PS128 is released. Preclinical science suggests that once inside the gut, PS128 balances the levels of the neurotransmitters dopamine and serotonin in key areas of the brain

Secondly, Neuralli MP is a medical probiotic. In other words, it contains a specific amount of a specific probiotic strain that has been shown by clinical studies to provide specific health benefits you can’t get just from eating food. Neuralli MP specifically addresses the dietary need of neurological conditions to support gut microbiome-to-brain signaling, through its action of being in the gut microbiome and altering brain neurotransmitters.

The PS128 probiotic strain in Neuralli MP has been put to the test in 8 published clinical studies with neurological conditions so far. Four involved people with autism. PS128 has also been studied with Parkinson’s disease, anxiety, and depression. 

In these trials, a majority of participants experienced one or more neurological health benefits. These included improvements in social interaction and levels of anxiety in children with autism, and less “off” time for patients with Parkinson’s disease (learn more about PS128 science here).

Most PS128 clinical study participants took 60 billion CFUs per day for neurological conditions, typically as capsules. PS128 has some ability to resist acidic conditions, and has also been used as a powder and mixed with food if needed. Each bottle of Neuralli MP includes a 30 day supply of this same clinical amount for neurological conditions (60 capsules at 30 billion CFUs per capsule).

Our commitment to quality

At Bened Life, we believe that people with invisible disabilities deserve safe and effective choices. We act on this belief by choosing strains that are well supported by peer-reviewed science. We also work hard to make sure that the product that lands on your doorstep is of the highest quality.

Here are four things about Neuralli MP that illustrate our commitment to quality:

Neuralli MP embodies Bened Life's commitment to quality

Made in the USA

It was important to us to use a factory in the USA for a number of reasons.

  1. Carbon footprint and heat exposure are reduced by manufacturing our products in the same country from which they are shipped.
  2. Stringent cGMP manufacturing processes are required by US FDA regulations.
  3. Third-party factory audits provide unbiased quality assurance.

Less travel, higher quality, more accountability. Making Neuralli MP in the USA (with global ingredients) is one of the many ways we put our customers ahead of our profits.

Packaged in CSP bottles

Neuralli MP is packaged in state-of-the-art 3-Phase Activ-Polymer™ CSP vials. CSP vials keep the inside of the bottle very dry and maintain maximum probiotic potency. Unlike lower-grade bottles that contain a small packet of desiccant, our bottles keep nearly all moisture away from the capsules. That means more of those precious PS128 CFUs you’ve invested in stay alive and active until you take them.

Packed in special acid-resistant capsules

Neuralli MP’s BioVXR capsules are exceptionally resistant to the acidic environment of the stomach, which protects the probiotic bacteria from inactivation. While there are many types of capsules that dissolve relatively slowly in acid, most dissolve at a similarly slow rate in the more neutral pH environment of the intestines.

The BioVXR capsules we use for all Bened Life products have the distinct advantage of dissolving very rapidly once they reach the intestines, releasing L. plantarum PS128 into the gut where it can do its work.

Protected against high-temperature travel

Neuralli MP can travel at temperatures up to 99°F safely, arriving at your doorstep with a minimum of 30 billion CFUs of PS128 per capsule, as promised. To make sure that each bottle is always delivered to you at full potency, we take these precautions:

  • Pack more CFUs into each capsule than the 30 billion listed
  • Ship expedited on ice in the USA during periods of extreme heat
  • Include a WarmMark temperature detector in the box so you can see if your probiotics have been exposed to temperatures above 99°F for an extended period. If they have, we will replace them.

Once you have Neuralli MP in-hand, we strongly recommend storing it in the refrigerator to maintain maximum potency. If you want to keep your open bottle out in a cool, dry place for up to a month where you can see it, that’s ok too!

We're raising the standard

At Bened Life, we are raising the standard for probiotics by creating Neuralli MP, a science-backed medical food. We are proud to stand behind the strength of the scientific studies of PS128.

Will Neuralli MP help you or your loved one? We invite you to find out by trying it for three months.


Recommended reading:

What to Expect in Your First Month Taking Neuralli MP

How to Get the Most Out of Neuralli MP

What is PS128?



Posted by Rob on

60mg daily direction. Split dosing, 30 q 12 hrs vs single dose qhs of 60? Since you don’t specify I gather it doesn’t matter when or how.

Posted by Herb Poulson on

Looking forward to receiving information on this new probiotic for PD.

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