12019 randomized double-blind placebo-controlled clinical study (Taiwan)
22021 randomized double-blind placebo-controlled clinical study (USA)
The probiotic medical food Neuralli® MP provides 60 billion CFUs of L. plantarum PS128TM, and delivers dietary management for autism and Parkinson's disease. Through dietary management, PS128TM supports clinically meaningful outcomes in autism and PD.
Three randomized, double-blinded, placebo-controlled studies using PS128TM showed reductions in anxiety or anxiety-like behavior in Autistic people.1-3 Physicians observed improvements in attention, communication and personal autonomy in a real-world study.4
In a pilot study with 25 Parkinson's disease patients taking PS128TM as dietary management alongside their own therapies, participants noted significant improvements in motor symptoms and quality of life.5
Neuralli® MP is a probiotic medical food containing the unique psychobiotic strain L. plantarum PS128TM at the same amount utilized in nine published clinical studies of neurological and mental health conditions.
PS128TM is a psychobiotic – “a live organism that when ingested in adequate amounts produces a health benefit in patients suffering from a neurological illness.”
Neuralli® MP is a medical food. The term medical food, as defined in section 5(b) of the Orphan Drug Act (21 U.S.C. 360ee (b) (3)) is "a food which is formulated to be consumed or administered enterally under the supervision of a physician and which is intended for the specific dietary management of a disease or condition for which distinctive nutritional requirements, based on recognized scientific principles, are established by medical evaluation".
In a single-arm pilot study, 25 PD participants took PS128TM alongside their existing medications for 12 weeks.
Read the clinical study and download the Parkinson’s fact sheet from the Resource Guide page:
Preclinical and clinical research suggests that PS128TM, the active ingredient in Neuralli® MP, has psychobiotic effects on the brain.
These psychobiotic effects are mediated by the gut-brain axis (GBA), allowing PS128TM to influence the brain without leaving the intestinal lumen.
Bened Life’s exclusive probiotic and postbiotic strains appear to work by sending signals from the gut to the brain.
Get everything you need to recommend Neuralli® MP to your patients with our Health Care Provider-exclusive Resource Guide.
At Bened Life, we’re guided by the microbiome’s power to influence health beyond digestion, with mechanisms that reach the brain and impact daily quality of life.
Our flagship product, Neuralli® MP, was developed with a singular goal: to translate rigorous research into a practical, evidence-based product for neurological care.
We work closely with researchers, clinicians, and caregivers to ensure our products are grounded in science, clinically relevant, and respectful of the patients they serve.
Whether you support Autistic individuals, or people with Parkinson’s disease, we’re here to assist your care with condition-specific fact sheets, patient-friendly materials, and concise summaries of the research behind Neuralli® MP.
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