Probiotic dietary support for anxiety & depression

Neuralli MP is a unique medical probiotic for your mental health condition

Neuralli® MP: Probiotics for mental health?

Anxiety and depression - they affect more than just your mind, because after all, our bodies are made of interconnected parts.

The brain, gut cells, and gut microbiome are all closely intertwined, and this gut-brain communication is a two-way street. In other words, what’s in your gut influences what happens in your brain.

The unique PS128 probiotic strain, found in Neuralli MP, can support gut microbiome-to-brain signaling in neurological conditions such as anxiety and depression.

How PS128 probiotics may help with anxiety & depression

Neuralli MP isn’t your average probiotic. It’s a medical probiotic that is intended for the dietary management of anxiety, depression, autism, and PD. It contains the unique psychobiotic strain L. plantarum PS128 that preclinical studies suggest can balance serotonin and dopamine in the brain.

Clinical studies of PS128 have noted the following:

  • Higher clinical effectiveness on anxiety of an SSRI when taken in combination with PS1281
  • Lower incidence of adverse reactions of an SSRI when taken in combination with PS1281
  • Improved mood scores in several depressed people after 8 weeks of PS128 in a small single-arm pilot study2

Want to learn more about PS128? See all 8 clinical studies.


What People Say

Anxiety much improved

This does seem to be working well. It's been about three months and the anxiety is much improved.

Lynn G.

Easier to regulate myself

I struggle with depression, anxiety, and mood regulation, and Neuralli boosts my baseline mood and reduces my anxiety, which makes it easier for me to regulate myself when triggered... Since my nervous system isn't as overwhelmed, I can use tools learned in therapy to regulate myself. With Neuralli and talk therapy, I'm definitely making progress.


Amanda V.

Closest thing to happy pills

I'm in STEM, and I normally wouldn't be caught dead making claims like this, but I must say, PS128 is the closest thing to happy pills I've ever found. I went from a chronically depressed person to an almost annoyingly happy person, while taking PS128. Thank you for everything.



Carlie s

I hear more laughter

We are only two weeks in, but I have seen an improvement in my son’s mood. I hear more laughter than I did before. So I am sure we are headed in the right direction.

 

Jennifer F.

 

My 11 year old daughter has generalized anxiety. We had to place her on medication a few years ago because her anxiety was causing such a disruption in her daily life. The medicine helps but she still struggles. I recently found Neuralli and decided to purchase it for her in addition to her medication. We saw a difference within a week. Her moods are balanced and she’s able to articulate her feelings with such clarity that she can work through them without spiraling. To say I’m grateful for Neuralli is an understatement. It has been life-changing for her and for our family.

 

C. M.

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Ingredients        Shipping Details

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Ingredients

L. plantarum PS128™, inulin, microcrystalline cellulose, silicon dioxide, magnesium stearate, and vegetable capsule.

Not manufactured with gluten, peanuts, soybeans, milk (including lactose), nuts, eggs, shellfish, fish, celery, mustard, sesame seeds, sulfur dioxide and sulfite, lupin and molluscs. Produced in an FDA-regulated, third-party audited, and cGMP-compliant facility that may process other products that contain these allergens or ingredients.

Each serving (2 capsules) contains at least 60 billion CFUs of L. plantarum PS128™.

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Shipping Details

You can expect to receive your order within 3-7 business days. Neuralli™ MP ships expedited via UPS in insulated packaging with ice packs. Orders not shipped by Wednesday will generally ship out by the following Monday to avoid weekend delays.

For urgent orders or special requests such as requiring a signature for delivery, please email [email protected].

Ice packs may arrive melted. They are added to reduce overall temperature exposure during travel, but Neuralli MP does not need to arrive cold. Neuralli MP can travel at temperatures up to 99° F and may arrive warm to the touch.

We recommend that Neuralli MP be refrigerated to guarantee the highest quality through its best by date. Each Neuralli MP capsule includes an extra amount of PS128™ added at the time of production to account for any loss that may occur during transport and storage.


International Shipments

Shipments outside the USA, including Canada, are subject to import taxes, customs duties, and/or fees imposed by the destination country. These charges are included at checkout and are the buyer’s responsibility.

Please find all Shipping Policies here.

One Bottle Purchase

1 Bottle
60 capsules/bottle
One-time purchase
$ 165/bottle

$ 165

To see if Neuralli MP works for you, please consider 2-month trial.
Neuralli MP contains the unique neurologically active probiotic strain L. plantarum PS128.
PS128 was administered for 2 or more months in all but one clinical study.**
**In studies of people with neurological conditions. 

Neuralli MP contains the unique neurologically active probiotic strain L. plantarum PS128.
PS128 was administered for 2 or more months in all but one clinical study.**
**In studies of people with neurological conditions. 

What People Say

I hear more laughter

We are only two weeks in, but I have seen an improvement in my son’s mood. I hear more laughter than I did before. So I am sure we are headed in the right direction.

Jennifer F.

Anxiety much improved

This does seem to be working well. It's been about three months and the anxiety is much improved.

Lynn G.

Easier to regulate myself

I struggle with depression, anxiety, and mood regulation, and Neuralli boosts my baseline mood and reduces my anxiety, which makes it easier for me to regulate myself when triggered... Since my nervous system isn't as overwhelmed, I can use tools learned in therapy to regulate myself. With Neuralli and talk therapy, I'm definitely making progress.

Amanda V.

Closest thing to happy pills

I'm in STEM, and I normally wouldn't be caught dead making claims like this, but I must say, PS128 is the closest thing to happy pills I've ever found. I went from a chronically depressed person to an almost annoyingly happy person, while taking PS128. Thank you for everything.

Carlie

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Clinically Studied Probiotic

Neuralli MP is the first gut-brain medical probiotic, formulated with a probiotic strain backed by 8 clinical studies with people with certain neurological conditions.

Clinically Relevant Formulation

Each bottle contains 60 capsules at 30 billion CFUs per capsule. Take 2 capsules per day to receive the same 60B CFU used in clinical studies of certain neurological conditions.

Highly Acid-Resistant

Neuralli MP’s probiotic bacteria and BioVXR capsules are engineered for acid-resistance. Take as capsules for maximum protection from stomach acid, or mix the powder into cold food or drink if needed.

Made in the USA

Less travel, higher quality, more accountability. Our US manufacturing process is one of the many ways we put our customers first.

Packaged in CSP Bottles

Neuralli MP is packaged in state-of-the-art 3-Phase Activ-Polymer™ CSP vials. CSP vials keep the inside of the bottle very dry and maintain maximum probiotic potency.

High-Temperature Travel Protected

Neuralli MP is packaged in state-of-the-art 3-Phase Activ-Polymer™ CSP vials. CSP vials keep the inside of the bottle very dry and maintain
maximum probiotic potency.

With global ingredients

It's easy to find out if Neuralli works for you

  1. Take 2 capsules a day
  2. Do this for three months.
  3. See what differences you notice in mood or movement.

Customers taking Neuralli MP have reported improved mood, less anxiety, and better ability to regulate overwhelming emotions.

Continuous and regular use of Neuralli MP provides the best results.

Looking for the best probiotic for anxiety?

There isn’t one “best” probiotic for anxiety or depression, but the unique strain L. plantarum PS128 is a promising option. It uses the gut microbiome-to-brain axis to help balance dopamine and serotonin in the brain (suggested by preclinical studies).

In a controlled study, patients with anxiety reported clinically satisfactory improvements in their anxiety symptoms after taking PS128 for two months alongside their meds.

This means that people with anxiety, who often have imbalanced serotonin and/or dopamine, may benefit from the dietary support provided by PS128 in Neuralli MP.

If you’ve been diagnosed with anxiety or depression, consider adding PS128 to your existing regimen or routine, and see if it helps you.

Neuralli MP is intended to be used under the supervision of a health care provider.

Did you know…?

How is Neurali MP different from a probiotic I can buy at the store?

Many probiotics on the market are dietary supplements and claim to support gastrointestinal function. Neuralli MP is different in two ways. It is a medical food, not a dietary supplement.

In addition, Neuralli MP, containing the probiotic L. plantarum PS128, is for the dietary support of specific neurological conditions such as autism, anxiety and depression. Studies of PS128 in autistic children, for example, have shown improvements in mood and attention, while a study in anxiety showed a reduction in reported anxiety.

Where can I find the clinical studies about PS128?

L. plantarum PS128, the active ingredient in Neuralli MP, has been clinically studied in Autistic people, as well as people with anxiety, depression, and Parkinson’s Disease. Summaries of the scientific research studies can be found here.

I have a medical condition. Can I take Neuralli MP?

As a medical food, Neuralli MP should be used under the supervision of your health care provider. Its active ingredient, PS128, has been studied in Autistic people and people with Parkinson’s, anxiety, and depression (see references here).

PS128 may play a role in modulating neurotransmitters such as dopamine and serotonin in some individuals. If you have concerns about this, please speak with your health care provider before starting or stopping Neuralli MP.

While each ingredient in Neuralli MP is self-affirmed as generally recognized as safe (GRAS), Neuralli MP has not been tested for safety and effectiveness in populations with other medical conditions. We recommend that you consult with your health care provider to decide if Neuralli MP is right for you.

Does Neuralli MP interfere with SSRI’s?

We always recommend consulting with your health care provider before starting any new medical food, supplement, or medication. A recent study that looked at the use of L. plantarum PS128 in patients with anxiety disorders found that the combination of anti-anxiety medication and PS128 led to fewer adverse events than taking the SSRI on its own. However, your experience may differ. Please take Neuralli MP under the supervision of your health care provider.

Visit our Neuralli MP FAQs page for more information!

What People Say

[When my husband] began using PS128 … I didn’t imagine I’d see any actual results. But just a month later, he regained strength in his fingers, and his hands stopped trembling enough for him to be able to replace his hearing aid batteries all by himself.

Caregiver of Parkinson’s patient

For the past few decades I’ve [struggled with nightmares and insomnia]. PS128 was only one of many “treatments” I tried, not hoping for any positive results. Yet after a few weeks taking PS128 twice a day, I was able to fall asleep without nightmares

Insomnia patient

With medication, I suffered badly with “on-off” phenomenon and motor complications. After the first month [taking PS128], the changes were subtle, but real: I could wear button-up shirts again… I could even button my left sleeve cuff using my right hand. PS128 gives me hope that I can keep my “normal days” longer.

Early-onset Parkinson’s patient