Neuralli® MP is a medical food for Parkinson's disease, formulated with PS128™ — the only probiotic strain shown to increase dopamine in preclinical models of PD‡ and clinically studied in people with Parkinson's.™.
The first probiotic shown to increase dopamine
Neuralli® MP is a medical food for Parkinson's disease, formulated with PS128™ — the only probiotic strain shown to increase dopamine in preclinical models of PD‡ and clinically studied in people with Parkinson's.
What happened when Parkinson’s patients took PS128™
In a single-arm pilot study, 25 people with Parkinson’s disease took PS128™ alongside their standard medication for 12 weeks.
PS128™ was studied as an add-on therapy to levodopa. Participants continued their existing Parkinson’s medications at stable doses throughout the study.
Lu et al., 2021. Open-label, single-arm pilot study. 25 participants. 12-week intervention.
What happened when Parkinson’s patients took PS128™
In a single-arm pilot study, 25 people with Parkinson’s disease took PS128™ alongside their standard medication for 12 weeks.
PS128™ was studied as an add-on therapy to levodopa. Participants continued their existing Parkinson’s medications at stable doses throughout the study.
Lu et al., 2021. Open-label, single-arm pilot study. 25 participants. 12-week intervention.
How does dopamine affect Parkinson's disease?
Parkinson’s disease is driven by the loss of dopamine-producing neurons in a part of the brain called the substantia nigra. As dopamine levels drop, motor symptoms increase.
Read More
Most PD treatments, including levodopa, work by increasing dopamine activity in the brain. But what if your gut could help your medication work better?
Research on the gut-brain axis shows that certain bacteria can influence neurotransmitter signaling — including dopamine signaling. PS128™, the probiotic strain in Neuralli® MP, is the first probiotic shown to increase dopamine levels in key brain regions in preclinical studies.‡
‡Liu et al., 2016; Liao et al., 2020; Lee et al., 2023 — preclinical studies in animal models
How does dopamine affect Parkinson's disease?
Parkinson’s disease is driven by the loss of dopamine-producing neurons in a part of the brain called the substantia nigra. As dopamine levels drop, motor symptoms increase.
Read More
Most PD treatments, including levodopa, work by increasing dopamine activity in the brain. But what if your gut could help your medication work better?
Research on the gut-brain axis shows that certain bacteria can influence neurotransmitter signaling — including dopamine signaling. PS128™, the probiotic strain in Neuralli® MP, is the first probiotic shown to increase dopamine levels in key brain regions in preclinical studies.‡
‡Liu et al., 2016; Liao et al., 2020; Lee et al., 2023 — preclinical studies in animal models
What the research shows
In preclinical studies, PS128™ has been shown to:
Read More
Increase dopamine levels in the striatum (the brain region most affected in PD)
Improve motor function in animal models of Parkinson’s disease
Reduce neuroinflammation and protect dopamine-producing neurons
Increase levels of BDNF, a protein that supports neuron health
These findings, published in peer-reviewed journals, suggest PS128™ works through the gut-brain axis to support dopamine signaling.‡
‡All findings from preclinical (animal) studies. Liu et al., 2016. Lee et al., 2023. Liao et al., 2020.
What the research shows
In preclinical studies, PS128™ has been shown to:
Read More
Increase dopamine levels in the striatum (the brain region most affected in PD)
Improve motor function in animal models of Parkinson’s disease
Reduce neuroinflammation and protect dopamine-producing neurons
Increase levels of BDNF, a protein that supports neuron health
These findings, published in peer-reviewed journals, suggest PS128™ works through the gut-brain axis to support dopamine signaling.‡
‡All findings from preclinical (animal) studies. Liu et al., 2016. Lee et al., 2023. Liao et al., 2020.
Your gut talks to your brain. PS128™ supports that conversation.
Hidden in your gut is a diverse ecosystem of trillions of microorganisms — the microbiome. This microbiome communicates with your brain through what scientists call the gut-brain axis.
Read More
PS128™ is a psychobiotic — a specific type of probiotic that provides a neurological health benefit through this gut-brain connection. Unlike probiotics designed for digestion, PS128™ was studied for its effects on the brain.
In preclinical studies, PS128™ influenced dopamine and serotonin levels in the brain — two neurotransmitters directly involved in the motor and mood symptoms of Parkinson’s disease.‡
You can’t get PS128™ from your diet or from a standard probiotic on the shelf. Neuralli® MP is a medical food formulated with 60 billion CFU of PS128™ — the same dose used in the clinical study of Parkinson’s disease, designed to be used under the supervision of your healthcare provider.
‡Preclinical studies in animal models.
Your gut talks to your brain.
PS128™ supports that conversation.
Hidden in your gut is a diverse ecosystem of trillions of microorganisms — the microbiome. This microbiome communicates with your brain through what scientists call the gut-brain axis.
Read More
PS128™ is a psychobiotic — a specific type of probiotic that provides a neurological health benefit through this gut-brain connection. Unlike probiotics designed for digestion, PS128™ was studied for its effects on the brain.
In preclinical studies, PS128™ influenced dopamine and serotonin levels in the brain — two neurotransmitters directly involved in the motor and mood symptoms of Parkinson’s disease.‡
You can’t get PS128™ from your diet or from a standard probiotic on the shelf. Neuralli® MP is a medical food formulated with 60 billion CFU of PS128™ — the same dose used in the clinical study of Parkinson’s disease, designed to be used under the supervision of your healthcare provider.
‡Preclinical studies in animal models.
What other PD patients are saying
What other PD patients are saying
Neuralli® MP
The 1st gut-brain probiotic medical food
Formulated with PS128TM to address the unique dietary requirements of Autistic people & people with Parkinson’s.
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Ingredients
Lactiplantibacillus plantarum PS128TM, microcrystalline cellulose, hypromellose, pectin, glycerol, silica, and magnesium stearate.
Each serving (2 capsules) contains at least 60 billion CFUs of L. plantarum PS128TM.
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Shipping Details
All Bened Life orders ship free within the USA.
You can expect to receive your order within 3-7 business days. Neuralli® products ship via UPS or USPS. Orders not shipped by Wednesday will generally ship out by the following Monday to avoid weekend delays.
You may receive your product in a box with or without cold packs, depending on the time of year and your geographic location. All Neuralli® products should be stored in their original bottles in the refrigerator upon arrival.
For urgent orders or special requests such as requiring a signature for delivery, please email hello@benedlife.com.
Bened Life is not responsible for stolen packages. If your delivery destination utilizes a grouped mailbox or delivery cannot be made to your door, please have your order shipped to a safe receiving location that is less prone to theft or tampering.
International Shipments
Shipments to Canada are subject to import taxes, customs duties, and/or fees imposed by the destination country, and are the buyer’s responsibility.
Neuralli Mood and Neuralli Cognition+ are currently not shipped outside of the US and Canada.
Please find all Shipping Policies here.
Neuralli® MP
The 1st gut-brain probiotic medical food
Formulated with PS128TM to address the unique dietary requirements of Autistic people & people with Parkinson’s.
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Did you know…?
How is Neuralli MP different from a probiotic I can buy at the store?
Probiotics that you buy at the store are typically dietary supplements claiming to promote gut health. Neuralli MP is not a dietary supplement designed to promote gut health. Neuralli MP is a medical food containing the probiotic L. plantarum PS128.
Through the ability of PS128 to support gut microbiome-to-brain communication, Neuralli MP provides dietary support for the following neurological conditions: autism, Parkinson’s disease, and anxiety. PS128 acts like a microbe-nutrient to meet the dietary needs of these conditions. PS128 cannot be obtained by dietary modification alone. While many bacteria may come through the diet via fermented foods, their possible benefits are unclear.
In preclinical studies, PS128 influenced levels of dopamine and serotonin in the brain. Certain neurological conditions such as autism, Parkinson’s and anxiety have dysregulated serotonin and dopamine in the brain.
Where can I find the clinical studies about PS128?
L. plantarum PS128, the active ingredient in Neuralli MP, has been clinically studied in Autistic people, as well as people with Parkinson's disease and anxiety. Summaries of the scientific research studies can be found here.
Can my child take Neuralli MP?
Children as young as 3 years of age have used 60 billion CFUs per day of PS128 in clinical studies. Please keep in mind that since each child is different, dosage may vary. Kindly review the labeling to ensure Neuralli MP is right for your child, and consult your health care professional.
Neuralli MP is a medical food intended to be used under the supervision of a health care professional.
I can’t take pills - how can I take Neuralli MP?
If swallowing the capsule is uncomfortable, you can open the shell and take the powder. (Take it all at once to guarantee its potency.) If you’d like, you can mix Neuralli MP powder into a cool drink or food of your choice. It should not be added to warm/hot foods or liquids. Read more here.
I have a medical condition. Can I take Neuralli MP?
As a medical food, Neuralli MP should be used under the supervision of your health care provider. Its active ingredient, PS128, has been studied in Autistic people and people with Parkinson’s and anxiety (see references here).
PS128 may play a role in modulating neurotransmitters such as dopamine and serotonin in some individuals. If you have concerns about this, please speak with your health care provider before starting or stopping Neuralli MP.
While each ingredient in Neuralli MP is generally recognized as safe (GRAS), Neuralli MP has not been tested for safety and effectiveness in populations with other medical conditions. We recommend that you consult with your health care provider to decide if Neuralli MP is right for you.
Can I take Neuralli MP if I’m pregnant or breastfeeding?
If you are breastfeeding or pregnant, we recommend speaking to your health care provider for guidance. They will have the best recommendations for you with your health history in mind.
Visit our Neuralli MP FAQs page for more information!
Neuralli® MP
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