Bened Life partners with health care providers, community leaders, and other experts who are looking for new tools to support gut-brain health in the people they serve.
Start a conversation with us about how to talk to your community about Neuralli, the first neurologically active medical probiotic:
Recommend the only
medical probiotic for
neurological conditions
Neuralli® MP is a gut-brain probiotic that works within the gut to enhance mood, mind and movement via the gut-brain axis.
It is specifically formulated as a medical food to assist in the dietary management of neurological conditions such as ASD, PD, and anxiety.
Educate yourself. Educate your patients.
Recommend Neuralli MP.
References
What the clinical research says about PS128
Neuralli MP provides 60 billion CFUs of L. plantarum PS128, a psychobiotic strain that affects signaling in the brain.
In four clinical studies conducted with Autistic people, those taking PS128 showed clinically meaningful improvements in several neurological and behavioral measures. (1-4)
In a pilot study with 25 Parkinson’s disease patients taking PS128 alongside their own therapies, participants noted significant improvements in motor symptoms and quality of life. (5)
Clinical improvements in anxiety (6) and depression (7) have also been noted.
What is Neuralli MP?
Neuralli MP is a medical probiotic containing the unique psychobiotic strain L. plantarum PS128 at the same amount utilized in 8 published clinical studies of neurological and
mental health conditions.
PS128 is a psychobiotic - “a live organism that when ingested in adequate amounts produces a health benefit in patients suffering from a neurological illness.”
Neuralli MP is a medical food. The term medical food, as defined in section 5(b) of the Orphan Drug Act (21 U.S.C. 360ee (b) (3)) is "a food which is formulated to be consumed or administered enterally under the supervision of a physician and which is intended for the specific dietary management of a disease or condition for which distinctive nutritional requirements, based on recognized scientific principles, are established by medical evaluation".
How PS128 works
Preclinical and clinical research suggests that PS128, the active ingredient in Neuralli MP, has both probiotic and psychobiotic effects.
Its psychobiotic effects are mediated by the gut-brain axis (GBA), allowing PS128 to influence
the central nervous system without leaving the intestinal lumen.
Neuralli MP facts at your fingertips
For Patients and Caregivers
Let’s work together!
Learn to talk to your community about Neuralli MP.
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No matter how you envision partnering with Bened Life, let’s start a conversation:
- Tell us about yourself with a quick 2 minute survey
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- If we’re a good fit for one another, we’ll set up a win-win partnership
Read the L. plantarum PS128 Clinical Studies for ASD
Each Neuralli MP serving contains the same amount of PS128 used in these studies.
Effects of L. plantarum PS128 on children with autism spectrum disorder in Taiwan: A randomized, double-blinded, placebo-controlled trial (2019)
Probiotic and oxytocin combination therapy in patients with autism spectrum disorder: A randomized, double-blinded, placebo-controlled pilot trial (2021)
L. plantarum PS128 and other probiotics in children and adolescents with autism spectrum disorder: A real-world experience (2021)
Probiotic intervention in young children with autism spectrum disorder in Taiwan: A randomized, double-blinded, placebo-controlled trial (2023)
Our clinical portfolio doesn’t stop there
PS128 has been studied in other neurological conditions, and additional research is ongoing.
Click here to review all PS128 published research on neurological conditions.
Our science team
At Bened Life, we stand on the shoulders of the microbiome experts at Bened Biomedical, our research-focused parent organization.
Bened Biomedical's R&D team of 6 PhD scientists is led by Professor Ying Chieh Tsai, whose distinguished 30+ year career in microbiology includes serving as the Director of Biochemistry at National Yang-Ming University (NYMU) School of Medicine in Taiwan.
Besides discovering L. plantarum PS128 and other psychobiotic strains, Bened’s scientists have collectively published more than 50 papers concerning the gut microbiome.
