by Katie Joll
One Early-Stage PD Patient’s Neuralli Experience
Acting out vivid dreams. Yelling during sleep. Flailing around and hitting the headboard. Rick had been doing these things during sleep for over 10 years, but what was happening?
We met Rick, a retired lawyer from Evans, Georgia, after he’d spent considerable time researching his condition and consulting with doctors. His textbook case of REM Sleep Behavior Disorder (RBD) was grim news - the condition is strongly linked to neurodegenerative diseases such as Parkinson’s and Lewy Body Dementia.
An avid researcher, Rick proactively looked for anything he could do to improve his health. Read on for his story about discovering Neuralli and how the medical probiotic helped improve his quality of life.
Disclaimers: This article describes one person's experience with Neuralli. Neuralli is a medical probiotic for the dietary management of gut microbiome to brain signaling in neurological disorders including Parkinson's disease. Neuralli contains the gut-brain probiotic PS128 which has been tested in one single-arm study of Parkinson's Disease patients. PS128 has not been studied in people with REM Sleep Behavior Disorder or people with a loss of the ability to smell. Bened Life makes no claims about Neuralli's effects on people with these symptoms. Neuralli is not a drug. Consistent with the Healthcare Nutrition Council's statement, a medical food can provide clinically meaningful improvements. The stated opinions of Rick are his alone and not Bened Life's.
“For 10 or 11 years, I've had episodes of REM Sleep Behavior Disorder,” says Rick. “I didn't know what it was. Acting out dreams, flailing about, hitting the headboard, hitting my wife, kicking, yelling, very vivid, disturbing dreams and acting out in response to that.”
“I finally needed to look it up. So I got on the internet and did some research. There's gotta be a name for it. And indeed there is; it's REM Sleep Behavior Disorder.”
Many people experience sleep disturbances, but RBD is a particularly pernicious condition that directly links with serious neurodegenerative conditions. Concerned with what he learned when he researched RBD, Rick had his condition confirmed with a sleep doctor, then decided to look further - did he have other symptoms that could point to a medical condition?
“I came back and started researching Parkinson's,” Rick says. “What are other signs and symptoms that would be coexisting at an early stage of the disease? And things that I had overlooked before as probably just normal signs of aging or had just kinda written off…”
Rick describes some of the symptoms: “Things like loss of sense of smell. Very common. I didn't know that. I just knew that I didn't smell things the way I used to. Didn't really smell food, cooking, etcetera. Didn't smell things outdoors, but I thought, oh, okay, I'm in my sixties. Maybe that happens. Getting dizzy when you stand up, you know, because of the drop of blood pressure…maybe that happens.”
“But when you put it all together, it points in one direction, in one direction only,” says Rick. Parkinson’s. “Then I made an appointment with a neurologist.”
Rick isn’t one to sit back and wait for suggestions - he was ready to take a proactive approach to his health and set his research skills to the task. “I guess kind of by virtue, through the miracle of the Internet, this ad started showing up from Neuralli,” Rick says.
As a careful researcher, Rick didn’t jump on Neuralli right away. “I kept seeing this ad, and I even researched Neuralli Probiotic Parkinson's scam to see if I got any hits, and I didn't,” says Rick.
What is Neuralli?
Neuralli is a medical probiotic containing the PS128 strain, and is formulated to meet the unique nutritional needs of people with neurological conditions, including Parkinson’s and ASD. PS128 appears to affect the gut microbiome to brain signaling that can be disrupted in these gut-brain conditions, and PS128 cannot be obtained in the diet.
Study participants with Parkinson’s reported significant improvements in motor symptoms and improved quality of life while taking PS128 along with their usual anti-Parkinsonian medication. PS128 appears to affect the gut microbiome to brain signaling that can be disrupted in these gut-brain conditions.
Rick decided to take the leap.“I said, you know, it is worth a try. The gut-brain axis connection with Parkinson's, my research had made that very clear that this is the cutting edge of thought in Parkinson's disease,” he says.
Parkinson’s and the Gut-Brain Axis
Emerging research suggests a strong link between the gut microbiome and the development of neurodegenerative conditions such as Parkinson’s disease. Parkinson’s is the fastest growing neurological condition in the world, with someone diagnosed in the United States every nine minutes.
While scientists are still piecing together the exact ways the gut microbiome influences the brain and the development of neurodegenerative conditions, they’ve made some fascinating discoveries. For example, researchers have found that early Parkinson’s symptoms can include dysfunction of the gut and that those symptoms can precede the onset of Parkinson’s by decades.
Rick says, “The connection seems to be just too clear and a possible avenue for prevention down the line and helping [with] some some of the symptoms that we deal with Parkinson's. So I started taking it to see what would happen.”*
“I Could Smell!”
Around 10 to 11 days into taking Neuralli, Rick had a startling revelation. “I go walking every morning and got up and started walking down the street from our neighborhood to the park, and I smelled a pine tree,” he says.
“I smelled them and I don't know that I'd ever smelled them before. Not for a long time, and I was struck by that. I could smell the grass, wet dirt, asphalt, bushes, things I had not been able to smell in an incredibly long period of time.”*
It was an emotional moment for Rick. “I didn't know whether to laugh or cry, and the only thing that was different, it was that I was taking this probiotic,” he says. “I came home, got changed, came out. I could smell breakfast cooking and coffee brewing. I haven't smelled that in years! I was giddy; I mean, it was really something!”*
Rick committed to at least trying Neuralli for three months to see how much of a difference it might make. Besides his newly-found sense of smell, he noticed other changes, too.
“I'm not nearly as dizzy or lightheaded when I stand up. I mean, before, I would stand up and have to grab hold of something for a few seconds just to stabilize. I don't have to do that anymore,”* says Rick.
“The REM sleep behavior has diminished. I don't remember having violent dreams and episodes*. There's some occasional vocalization in my sleep. You know, basically just gibberish… but nothing like it was before. And I'm not on any Parkinson's medication. I take no multivitamins, etc. But there's only one thing that was different between then and now, and that's the Neuralli,” he says.
“From my perspective, with these prodromal symptoms of Parkinson's, it (Neuralli) makes a tremendous difference.”*
A New Routine With Neuralli
Neuralli is now part of Rick’s everyday routine. He isn’t on any medications for Parkinson’s, but he does maintain close contact with his neurologist to monitor his condition. “My neurologist is well aware of the fact that I am taking Neuralli and heartily approves,” he says.
For anyone with early-stage Parkinson’s, Rick encourages them to consult with their own physicians and consider trying Neuralli. “The first steps that someone should take, if they're totally unfamiliar at all with Parkinson's research and the gut-brain axis, they should start there and start doing some basic research. So with that basic knowledge, maybe if I change the bacteria, my microbiome in my gut, this can have an impact on my day-to-day life.”
Rick understands that some people may be skeptical. “I understand folks' reluctance,” he says. “That's why I researched, ‘internet probiotic Parkinson's scam.’ I mean, I researched those words, kind of half expecting to get a hit. It didn't! I was skeptical too. I tried it, and … improved and stayed improved down the line. I committed to a three-month trial, and I would recommend that to anybody, just to see what happens.”
“You take it once a day… and that's it. And it has made this huge difference in my life.”
*Disclaimers: This article describes one person's experience with Neuralli. Neuralli is a medical probiotic for the dietary management of gut microbiome to brain signaling in neurological disorders including Parkinson's disease. Neuralli contains the gut-brain probiotic PS128 which has been tested in one single-arm study of Parkinson's Disease patients. PS128 has not been studied in people with REM Sleep Behavior Disorder or people with a loss of the ability to smell. Bened Life makes no claims about Neuralli's effects on people with these symptoms. Neuralli is not a drug. Consistent with the Healthcare Nutrition Council's statement, a medical food can provide clinically meaningful improvements. The stated opinions of Rick are his alone and not Bened Life's.
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Here are some things that set Neuralli apart:
- Neuralli is the first neurologically active medical probiotic. A novel probiotic strain clinically proven to provide a neurological health benefit.
- Each bottle of Neuralli contains 60 capsules at 30 billion CFUs per capsule. Neuralli is meant to be taken at the clinical dosage of 2 capsules per day for neurological health benefits. For mental health benefits, Neuralli may be taken at 1-2 capsules per day.
- Neuralli is made in the USA in an FDA-regulated, third-party audited, and cGMP-compliant facility.
- Neuralli is packaged in 3-Phase Activ-Polymer™ CSP vials designed to keep the inside of the bottle very dry to maintain maximum potency.
- Neuralli capsules include time-release technology for added gut deliverability.
- Neuralli can travel at temperatures up to 99°F without affecting potency.
You can expect to receive your order within 3-7 business days. Neuralli™ ships expedited via UPS in insulated packaging with ice packs. Orders not shipped by Wednesday will generally ship out by the following Monday to avoid weekend delays.
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Ice packs may arrive melted. They are added to reduce overall temperature exposure during travel, but Neuralli does not need to arrive cold. Neuralli can travel at temperatures up to 99° F and may arrive warm to the touch.
We recommend that Neuralli be refrigerated to guarantee the highest quality through its best by date. Each Neuralli capsule includes an extra amount of PS128™ added at the time of production to account for any loss that may occur during transport and storage.
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Neuralli contains the unique neurologically active probiotic strain L. plantarum PS128.
PS128 was administered for 2 or more months in all but one clinical study**.
**In studies of people with neurological conditions.
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L. plantarum PS128TM , inulin, microcrystalline cellulose, silicon dioxide, magnesium stearate, and vegetable capsule (hydroxypropyl methylcellulose and water).
Not manufactured with gluten, peanuts, soybeans, milk (including lactose), nuts, eggs, shellfish, fish, celery, mustard, sesame seeds, sulfur dioxide and sulfite, lupin and molluscs. Produced in an FDA-regulated, third-party audited, and cGMP-compliant facility that may process other products that contain these allergens or ingredients.
Each serving (2 capsules) contains at least 60 billion CFUs of L. plantarum PS128TM.
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The price shown above reflects the application of the discount code 'PNT25' on the checkout page.
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