Do you persistently feel sad, hopeless, not interested in anything, or stressed? A feeling of suffocation leads to a variety of breakdowns. You are not alone!

Approximately 5% of adults suffer from depression, and 20 out of every 100 people develop depression at some point in their lifetime, eventually becoming a significant public health concern worldwide.

There is no quick fix to negative thoughts since they can hit you when taking care of your family, at work, or during/after maternity. However, do you know this is happening because you have an inflamed body due to unhealthy gut?

The Gut and Major Depressive Disorder (MDD)

Called the Second Brain - having the second largest number of neurons besides our brain, our gut is connected to the brain via the Gut-Brain Axis (GBA), explaining why we have “butterflies” in our stomachs when we are nervous.

Unfortunately, it appears that low-grade chronic neuroinflammation plays a critical role in forming the basis for the interaction between stress, gut microbiota, and major depressive disorder (MDD).

Interestingly, research indicates that treating the gut with Neurobiotics like PS128™ can help reduce inflammation and balance gut microbiota, significantly improving the quality of life of those with depressive disorder.

Stressors in Life

Stress is a normal part of life -- but some changes in health, career, family, and lifestyle cause more anxiety than the others. Have you ever thought what are the stressors of your life?

We all wear many hats in our life, both men and women. A woman can be a mother to her children, an employee to the company, a manager to a team, a caregiver to seniors, or a wife to her husband. According to WHO, women are 2x more likely to be diagnosed with depression than men. Being a mom is a long journey for women, starting from pregnancy, going into labor, until the birth of the baby. However, the journey hasn’t yet ended - “postpartum blue” or “maternity blue” is preparing to take advantage of every opportunity to cause unstable emotions, resulting in postpartum depression.

Rarely, an extreme mood disorder called postpartum psychosis also may develop after childbirth. Differences in hormones, social roles, and life stress are slowly poisoning their mental health, eventually contributing to depression.

Men is in no better situation. Do you think only women develop depression? Assumptions about traditional gender roles are critical barriers to diagnosing men with depression. Why? Traditional masculines can make it even more challenging to acknowledge and express feelings, making them less likely to seek help for their symptoms.

Japan has a famous phenomenon highlighting the importance of tackling mental health - “May Blues” or “gogatsubyō”. A transition in life makes it hard to adapt, whether you are a fresh graduate, returning from maternity leave, or holiday/vacation. Entering or re-entering the workforce is a crucial factor causing depression. Internal stress (e.g., anxiety) + external environment (e.g., monsoon season) often lead us into a worse situation and, eventually, get out of hand.

How much do you score from self-quiz for depression? If you score more than five, then it is time to pay attention and love yourself.

Mood disorder is a class of severe mental illnesses describing all types of disorders like depression, anxiety disorder, bipolar, manic depression, etc. You might wonder: what is a mood disorder, and how do we distinguish between a “normal feeling down” and a “mood disorder”?

Emotions like anxiety, feeling down, unhappy, stressed, angry, etc., all can be related to daily stress and frustration, traumatic events, or one’s personality. The difference between a normal feeling down and a mood disorder is “frequency” and “time duration.”

Theoretically speaking, negative emotions will fade away with time; it won’t be a long-lasting emotion. If the emotion carries on, then there is a chance of developing into a emotional disorder.

Low levels of serotonin will cause depression, anxiety, insomnia, and other mood problems. Seeking medical advice is a general practice, but what if there is a natural therapy rather than a medication? PS128™ is a novel psychobiotic that balances the “happy hormones” like serotonin and dopamine, cortisol, and other molecules that affect mind, mood, and movement.

Happier Gut, Healthier Mind

Can probiotics help with Major Depressive Disorder (MDD)?

Recently, probiotics have become a popular treatment for gut-related issues, as disruptions to gut microbiota balance may contribute to a wide range of health concerns, even mental health. One of the factors affecting your gut health is diet. An unhealthy diet destroys gut bacterial composition and reduces bacterial diversity and richness, resulting in gut inflammation.

Not all probiotics are equivalent; only specific researched strains like Neurobiotics have an impact on improving mental health symptoms. A medical probiotic can modulate neurotransmitters (dopamine and serotonin) that affect appetite, mood, or sleep and reduce neuroinflammation in your body.

Interestingly, research indicates that Lactobacillus plantarum PS128™ appears to improve anxiety symptoms and reduce adverse reactions.

The Neurobiotic - L. plantarum PS128

Probiotics are live microorganisms, which can tip the balance of the gut microbiome, and are known for providing health benefits. But neurobiotic strains like L. plantarum PS128 - naturally isolated from the fermented vegetable Fu-Tsai - go further providing benefits for those with Autism, ADHD, Parkinson's disease, and Depression.

“Unlike pharmaceuticals merely overpowering our bodies’ functions, the fermented food-derived PS128 gently works with our microbiome.”

PS128™ clinical data on depression

The efficacy of PS128™ preclinical studies on depression was proven in a recent clinical study. After consuming PS128™, depressive severity in patients with MDD significantly ameliorated, and among them, nearly 3/4 are females.

Bened Life

Derived from the Latin root “benedicere”, which means “blessed” or “full of blessings”, the Bened Life team comes from all walks of life, united by a common mission to advance science, improve health, and build a sensory inclusive world. And KultureCity, an NGO for neurodiverse people, has been a partner for our dream.

Bened Life is dedicated to promoting neurological and mental health with pharma-grade brain probiotics, backed by over 30 years of research experience, and clinical studies. With Neuralli, we are making meaningful impact on individuals and families globally.

“Let’s have a world where one can thrive regardless of how one perceives the world -
a world where we all can all truly live a bened life.”

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Neuralli® MP

Each serving (2 caps.) of Neuralli MP contains 60 billion CFUs of PS128 - a specific amount one can’t get from eating food alone. Neuralli MP is a safe and natural product - it does not contain any additives and is free of 14 common allergens. It is also considered as "generally recognized as safe" (GRAS) to consume.

Regulate dopamine
and serotonin

Reduce Anxiety

Significantly improve
neurological disorders

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How do I use the pills as a powder?

Swallowing the pills is not the only way to take Neuralli MP - you can also use the contents of the capsules in powder form. Neuralli MP capsules can be twisted and then pulled open.

Open the capsules over the cold food or drink that you wish to mix it with so you don’t lose any of the powder. We do not recommend mixing Neuralli MP powder into hot foods or liquids, as it will decrease the potency of Neuralli MP.

Mix thoroughly and consume within a few minutes for best results.

“The first and leading gut-brain medical probiotic from the United States for ADHD, Autism, Depression, and Parkinson’s.”

Neuralli MP can be taken as easy-to-swallow capsules or opened and mixed into cold liquids or foods.

Single - Neuralli MP

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**VAT & custom duties not included, see checkout page for charges.
To see if Neuralli works for you, please consider 2-month trial or more.
Neuralli contains the unique neurologically active probiotic strain L. plantarum PS128.
PS128 was administered for 2 or more months in all but one clinical study**.

**In studies of people with neurological conditions.

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What People Say

So Thankful to Find This

[My daughter] said she feels more even-keeled, more positive, better rested and less anxious. I am noticing a significant improvement in her ability to handle stress which would normally result in meltdowns. This probiotic really seems to be making a difference for her.

K. T.

Honestly Life Altering

Amazing product. It has improved my mood tremendously and allowed me to find more joy in each day. Highly recommend. Worth every penny.

Laura N

More Laughter

We are only two weeks in, but I have seen an improvement in my son’s mood. I hear more laughter than I did before. So I am sure we are headed in the right direction.

Jennifer F

Thank You!

At one month in I am amazed at the positive benefits my body seems to be getting.

Barbara A.

Did you know…?

What is Neuralli MP?

Neuralli MP, as its name suggests, is a medical probiotic specific to neurological and mental health. Neuralli MP’s active ingredient, L. plantarum PS128, is able to provide clinically meaningful improvements for people with neurological conditions such as ASD. Neuralli MP is a medical probiotic because it is a medical food, which is intended for use under the supervision of a physician and provides dietary management for neurological conditions such as ASD.

Can I take Neuralli MP with other supplements or probiotics?

Neuralli MP can be taken with most other probiotics. Use caution when combining Neuralli MP with any other substance that affects levels of serotonin, dopamine, or cortisol. Contact your health care provider if you have any concerns about interactions with other products you are taking or if you have any health conditions.

How do I take Neuralli MP?

Autistic people can take 2 capsules a day - which contains the same serving used in clinical studies. If swallowing the capsule is uncomfortable, you can open the shell and take the powder. (Take it all at once to guarantee its potency.) If you’d like, you can mix Neuralli MP powder into a cool drink or food of your choice. It should not be added to warm/hot foods or liquids.

How long will it take to notice results?

Noticeable results varies between individuals. 70% of people who took Neuralli MP for 2+ months improved their quality of life, based on 70 customer survey respondents. You may notice changes within the first week, or it may require 2 or more months to notice results, as evidenced by clinical studies of PS128.

Further reading:


Can probiotics improve mental health?


Do probiotics help with anxiety?


Probiotics for stress