Introducing Neuralli

Introducing Neuralli™ Medical Probiotic

Since 2012, medical science has exploded with new research into the gut microbiome. From gastrointestinal function, to weight gain, to food allergies, we now know that gut microbes have a powerful influence on our physical health. No wonder so many people choose to take probiotics as supplements and in foods. 

But you might not know that the gut microbiome also plays a significant role in neurological and mental health. Levels of "happy brain hormones" like dopamine and serotonin can be influenced by gut bacteria via gut-brain signaling. These same neurotransmitters are imbalanced in certain neurological conditions like autism spectrum disorder (ASD) and Parkinson’s Disease (PD). 

Introducing Neuralli, the only probiotic medical food formulated to address the unique nutritional needs of people with neurological conditions such as ASD and PD. How? By supporting healthy gut-microbiome-to-brain signaling. 

Each serving, two capsules, of Neuralli contains 60 billion CFUs of L. plantarum PS128, a unique probiotic strain that is neurologically active. Since 2015 when our parent company Bened Biomedical introduced PS128 to the world, 35+ million servings have been sold worldwide. In the years since then, the neurological health benefits of PS128 have been studied in many human clinical trials. Neuralli stands on a rich history of PS128 science and helping people with neurological conditions.

Neuralli is a neurologically active probiotic ideal for autistic people, people with Parkinsons and people with mental health challenges

Neuralli is the first neurologically active medical probiotic

If you’re not familiar with the many probiotic strains out there, you might think all probiotics are pretty much the same. Is there really any difference between Neuralli and yogurt with “live cultures” or a supplement for gut health

There is! 

First of all, Neuralli is neurologically active. The active ingredient in Neuralli is the live probiotic bacterial strain L. plantarum PS128. When the acid-resistant Neuralli capsule reaches your gut, PS128 is released. Its beneficial effects, as demonstrated in multiple clinical trials, may be due to mechanisms demonstrated in preclinical studies. These studies suggest that taking PS128 balances the levels of the neurotransmitters dopamine and serotonin in key areas of the brain. 

Secondly, Neuralli is a medical probiotic. In other words, it contains a specific amount of a specific probiotic strain that has been shown by clinical research to provide specific health benefits you can’t get just from eating food. 

The PS128 probiotic strain in Neuralli has been studied in 12 published clinical trials so far. Three trials involved people with autism, and one had participants with Parkinson’s disease. In the four trials, a majority of participants experienced one or more neurological health benefits. These included improvements in social interaction and levels of anxiety in children with autism, and less “off” time for patients with Parkinson’s disease (learn more about Neuralli science here). 

These clinically meaningful benefits suggest that PS128 provides a unique dietary support to the gut microbiome’s signaling to the brain. While PS128 was originally derived from a fermented food, it’s necessary to use the high concentration of PS128 provided by Neuralli capsules or powder to provide this dietary support.

In most clinical studies of PS128, patients took 60 billion CFUs per day, either as capsules or as powder. PS128 is resistant to stomach acid, allowing it to be used as a powder mixed with food or drink if needed. Each bottle of Neuralli includes a 30 day supply of this same clinical serving size for neurological health benefits (60 capsules at 30 billion CFUs per capsule).

Neuralli PS128 probiotic comes as a capsule and can also be used as a powder

Our Commitment to Quality

At Bened Life, we believe that people with invisible disabilities deserve safe and effective choices when it comes to neurological health. We act on this belief by developing strains that are well supported by peer-reviewed science. We also work hard to make sure that the product that lands on your doorstep is of the highest quality. Here are a few things about Neuralli that illustrate our commitment to quality:

Made in the USA

It was important to us to produce Neuralli in the USA for a number of reasons.

  • Carbon footprint and heat exposure are reduced by manufacturing Neuralli in the same country from which it is shipped.
  • Our manufacturing partner is FDA-regulated and required by law to adhere to stringent cGMP manufacturing processes.
  • Our factory is audited by third-parties for unbiased quality assurance.

Less travel, higher quality, more accountability. Our US manufacturing process is one of the many ways we put our customers first.

Packaged in CSP bottles

Neuralli is packaged in state-of-the-art 3-Phase Activ-Polymer™ CSP vials. CSP vials keep the inside of the bottle very dry and maintain maximum probiotic potency. Unlike lower-grade bottles that contain a small packet of desiccant, our bottles keep nearly all moisture away from the capsules. That means more of those precious PS128 CFUs you’ve invested in stay alive and active until you take them.

Packed in special acid-resistant capsules

Neuralli’s BioVXR capsules are exceptionally resistant to the acidic environment of the stomach, which protects the probiotic bacteria from inactivation. While there are many types of capsules that dissolve relatively slowly in acid, most dissolve at a similarly slow rate in the more neutral pH environment of the intestines. The BioVXR capsules we have chosen for Neuralli have the distinct advantage of dissolving very rapidly once they reach the intestines, releasing L. plantarum PS128 into the gut where it can do its work.

Protected against high-temperature travel

Neuralli will arrive at your doorstep with a minimum of 30 billion CFUs of PS128 per capsule, as promised. To make sure that each bottle of Neuralli is always delivered to you at full potency, we take these precautions:

  • Pack more CFUs into each capsule than the 30 billion listed to account for CFU lost in transit or storage. 
  • Ship expedited, and with ice packs in the USA during the summer.
  • Insulate with robust, 1 1/2" thick, 100% recyclable, Climacell thermal panels.

Once you have Neuralli in-hand, we highly recommend storing it in the refrigerator to maintain maximum potency through its best-by date. 

We're Raising the Standard

At Bened Life, we are raising the standard for probiotics by creating Neuralli, a science-backed medical food. We are proud to stand behind the strength of the science of PS128. 

Will Neuralli help you or your loved one? We invite you to find out by trying it for one to three months.


Recommended reading:

Ways to Take Neuralli

What to Expect in Your First Month Taking Neuralli

Meet Izzy - The First Person to Take PS128



Posted by Rob on

60mg daily direction. Split dosing, 30 q 12 hrs vs single dose qhs of 60? Since you don’t specify I gather it doesn’t matter when or how.

Posted by Herb Poulson on

Looking forward to receiving information on this new probiotic for PD.

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